Fig. 6: Hierarchical clustering of differentially expressed genes between control groups and the AeDHPAAS RNAi group.

a Hierarchical clustering of differentially expressed development-related genes. b Hierarchical clustering of differentially expressed cuticle protein-related genes. c Hierarchical clustering of differentially expressed genes involved in chitin metabolism. d Hierarchical clustering of differentially expressed genes involved in lipid metabolism pathways. e Hierarchical clustering of rhythmic lipid transport-related genes. Red indicates higher expression, while blue and green indicate lower expression relative to the mean value for each gene. Source data are provided as a Source Data file. DEPC treatment of adult mosquitoes with DEPC water, GUS treatment of adult mosquitoes with gus‑dsRNA, DS treatment of adult mosquitoes with AeDHPAAS‑dsRNA.