Fig. 6: High-level production of 4-M-PDO via further metabolic engineering and process optimization.
From: Microbial synthesis of branched-chain β,γ-diols from amino acid metabolism

a The composition of plasmid pAC-Ilv2c-Aro10-IlvCD6803. b The distribution profile of diols in engineered strain MR4Δ-06. c The titer of diols and their precursors in strain MR4Δ-06. d The titer of isobutyraldehyde, 3-H-4-MP-2-one, 4-M-PDO and the proportion of diols. e OD600 and the concentration of glucose of MR4Δ−06 in the fed-batch fermentation. The average and standard deviation are obtained from three biological replicates. Source data are provided as a Source Data file.