Fig. 5: Scope for E-selective C(sp2)–H perfluoro-tert-butylation of styrene derivatives. | Nature Communications

Fig. 5: Scope for E-selective C(sp2)–H perfluoro-tert-butylation of styrene derivatives.

From: Selective radical-type perfluoro-tert-butylation of unsaturated compounds with a stable and scalable reagent

Fig. 5

The reaction shows excellent functional group tolerance and is compatible in late-stage functionalization. Reactions were done in 0.2 mmol scale using standard conditions unless otherwise noted. All the yields above were isolated yields for E-isomer. a 2 equiv. CaCO3 was added as base. b 2 equiv. DtBP was added as base.

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