Table 1 Demographic data for the trial and control cohorts

From: Prolonged normothermic perfusion of the kidney prior to transplantation: a historically controlled, phase 1 cohort study

Variable

NKP1 (n = 36)

Control cohort (n = 72)

Timings

 First CIT, hours, median (IQR)

8.57 (3.49)

8.88 (3.16)

 Normothermic machine perfusion time, hours, median (IQR)

5.83 (4.54)

-

 Second CIT, minutes, median (IQR)

68.41 (30.00)

-

 Total preservation time, hours, median (IQR)

15.74 (6.35)

8.88 (3.16)

Recipients

 Age, years, mean (sd)

59.2 (12.0)

53.8 (14.4)

 Sex, male, n (%)

24/36 (67%)

46/72 (64%)

 BMI, mean (sd)

28.1 (5.8)

27.3 (5.1)

 Dialysis modality, n (%)

HD

22/36 (61%)

46/72 (64%)

PD

10/36 (28%)

9/72 (13%)

Predialysis

4/36 (11%)

17/72 (24%)

 Duration of dialysis, years, mean (sd)

2.3 (2.0)

1.9 (2.2)

 Previous transplant, n (%)

8/36 (22%)

12/72 (17%)

 History of diabetes, n (%)

12/36 (33%)

12/72 (17%)

 Induction immunosuppression, n (%)

Alemtuzumab

26/36 (72%)

52/72 (72%)

Basiliximab

10/36 (28%)

20/36 (28%)

Donors

 Donor age, years, mean (sd)

54.0 (15.8)

55.0 (15.1)

 Donor type, n (%)

DBD

20/36 (56%)

40/72 (56%)

DCD

16/36 (44%)

32/72 (44%)

 Donor sex, male, n (%)

23/36 (64%)

40/72 (56%)

 Donor BMI, mean (sd)

28.3 (6.4)

27.3 (5.9)

 Donor history of hypertension, yes, n (%)

18/36 (50%)

18/72 (25%)

 Donor risk index (DRI), mean (sd)

1.36 (0.59)

1.35 (0.55)

 HLAMM group, n (%)

1

0/36 (0%)

4/69 (6%)

2

9/36 (25%)

18/69 (26%)

3

19/36 (53%)

28/69 (41%)

4

8/36 (22%)

19/69 (28%)

  1. Source data are provided as a Source Data File.
  2. CIT cold ischaemic time, BMI body mass index, HD haemodialysis, PD peritoneal dialysis, DBD death by neurological criteria, DCD donation after circulatory death, DRI donor risk index (2019 UK Kidney Donor Risk Index), HLAMM Human leucocyte antigen mismatch, IQR interquartile range, SD standard deviation.