Table 1 Population characteristics in the two groups in the randomised trial

Mean age (SD)

46.1 (10.5)

46.4 (9.14)

46.3 (9.85)

Sex

Female

101 (85.6%)

99 (85.3%)

200 (85.5%)

Male

17 (14.4%)

17 (14.7%)

34 (14.5%)

Mean weight in kg at baseline (SD)

102 (19.4)

102 (21.5)

102 (20.4)

Mean body mass index at baseline (SD)

36.8 (6.49)

36.8 (7.47)

36.8 (6.98)

Utility at baseline*

Mean (SD)

0.474 (0.272)

0.482 (0.237)

0.478 (0.255)

Median [min, max]

0.532 [−0.246, 0.985]

0.516 [−0.156, 0.985]

0.530 [−0.246, 0.985]

Primary symptom (participant-selected)

Pain

14 (11.9%)

14 (12.1%)

28 (12.0%)

Breathlessness

17 (14.4%)

20 (17.2%)

37 (15.8%)

Fatigue

66 (55.9%)

60 (51.7%)

126 (53.8%)

Anxiety/depression

2 (1.7%)

1 (0.9%)

3 (1.3%)

Other

19 (16.1%)

21 (18.1%)

40 (17.1%)

Ethnicity

South Asian

5 (4.2%)

5 (4.3%)

10 (4.3%)

Other Asian or Asian British background

0 (0%)

5 (4.3%)

5 (2.1%)

Black, African, Caribbean or Black British

2 (1.7%)

0 (0%)

2 (0.9%)

White

105 (89.0%)

106 (91.4%)

211 (90.2%)

Other or mixed ethnic group

6 (5.1%)

0 (0%)

6 (2.6%)

Index of multiple deprivation (quintile)

Quintile 1 (most deprived)

13 (11.0%)

18 (15.5%)

31 (13.2%)

Quintile 2

22 (18.6%)

22 (19.0%)

44 (18.8%)

Quintile 3

29 (24.6%)

16 (13.8%)

45 (19.2%)

Quintile 4

28 (23.7%)

23 (19.8%)

51 (21.8%)

Quintile 5 (least deprived)

26 (22.0%)

37 (31.9%)

63 (26.9%)

Employment status at baseline

Full-time employment

50 (42.4%)

51 (44.0%)

101 (43.2%)

Part-time employment

35 (29.7%)

34 (29.3%)

69 (29.5%)

Retired

4 (3.4%)

2 (1.7%)

6 (2.6%)

Student

0 (0%)

1 (0.9%)

1 (0.4%)

Unemployed

7 (5.9%)

10 (8.6%)

17 (7.3%)

Other

22 (18.6%)

18 (15.5%)

40 (17.1%)

Mean healthcare resource use cost at baseline (SD)

£652 (650)

£893 (1540)

£773 (1190)

Productivity loss at baseline

Mean hours missed per week (SD)

9.18 (13.3)

11.7 (15.2)

10.5 (14.3)

Mean productivity cost per week (SD)

£139 (200)

£170 (226)

£154 (214)