Fig. 1: Sr6 gene and SR6 protein structures.
From: Divergent molecular pathways govern temperature-dependent wheat stem rust resistance genes
A Sr6 gene structure showing positions of EMS-induced SNPs identified in mutants. SNP positions are shown by red bars labelled with mutant number, and altered amino-acid positions are given. Shaded areas are UTRs. Domain encoding regions are indicated: CC coiled-coil, NB-ARC nucleotide binding (APAF-1, R proteins and CED-4), LRR leucine-rich repeat. B Full-length structure of SR6 protein, its zinc ion binding region, and ATP binding region are predicted by AlphaFold3. The full-length structure comprises three subdomains: the BED motif (light pink shaded) containing the N-terminal subdomain (yellow shaded), the NB-ARC domain (salmon shaded), and the LRR domain (green shaded).
