Table 1 Clinical characteristics of systemic sclerosis patients and healthy donors for scRNA-seq analysis
Systemic sclerosis | Healthy donors | |||||
|---|---|---|---|---|---|---|
Overall profiles | ||||||
Number | 21 | 6 | ||||
Age (Years) | 64.0 | (56.5–75.0) | 65.5 | (61.3–73.5) | ||
Male/Female | 5/16 | 2/4 | ||||
Duration (years) | 7.0 | (4.5–18.0) | ||||
Skin and organ involvement | ||||||
Skin | Skin sclerosis | 21 | 100% | |||
Diffuse/Limited cutaneous | 3/18 | 14/86% | ||||
Raynaud’s phenomenon | 21 | 100% | ||||
Digital ulcer | 5 | 23.8% | ||||
Interstitial lung disease | 12 | 57.1% | ||||
Scleroderma renal crisis | 4 | 19.0% | ||||
Pulmonary artery hypertension | 3 | 14.3% | ||||
Chronic intestinal pseudo-obstruction | 2 | 9.5% | ||||
Autoantibody | ||||||
Anti-RNA polymerase III | 9 | 42.9% | ||||
Anti-topoisomerase I | 3 | 14.3% | ||||
Anti-centromere | 7 | 33.3% | ||||
Anti-nuclear (nucleolar pattern) | 2 | 9.5% | ||||
