Fig. 5: Derivatizations and scale-up synthesis.

A Scale-up synthesis. B Decorations of drug molecules, (i) 1.2 equiv. related amine, 3 equiv. NaBH₃CN and 4 equiv. anhydrous MgSO₄. (ii) 1.2 equiv. hydrazide, anhydrous MeOH. [Pd] = PdCl₂(PPh₃)₂. C Boron-involved transformations. D Enabling streamlined drug synthesis.