Fig. 4: Genes associated with metabolites based on rare variants.
From: Pleiotropic and sex-specific genetic mechanisms of circulating metabolic markers

a Stacked bar plot showing the number of significant associations (x-axis) with genes identified through whole-exome sequencing-based gene burden tests (y-axis), coloured by metabolite category. b Grouped scatterplot, showing the -log10(p-value) of Bonferroni-corrected significant genes on the y-axis, grouped by category on the x-axis, with the dot colours also reflecting category. The top three most significant genes per category are annotated.