Table 1 Demographic data and post-implantation outcomes

From: Refining centromedian nucleus stimulation for generalized epilepsy with targeting and mechanistic insights from intraoperative electrophysiology

Pt. No.

Age (y)

Sex

Epilepsy duration (y)

Months implanted/ stimulated

Implanted depth along chosen trajectory

Epilepsy diagnosis

Seizure type

Seizure frequency

Before RNS

After RNS

RNS01

45

F

20

12/7

−1 mm

−1 mm

JAE

Absence

~50/day

50–75% reduction

GTC

~1–2/week

None in last 7 mo

RNS02

26

F

11

11/5

−3.5 mm

−3.5 mm

IGE

Absence

~1–10/day

50–75% reduction

Myoclonus

~1−10/day

50–75% reduction

GTC

~2–3/mo

None in last 2 mo

RNS03

21

F

8

10/8

−1 mm

−1 mm

JAE

Absence

~40/day

50% reduction

  1. CM centromedian nucleus of the thalamus, GTC general tonic-clonic seizure, JME juvenile myoclonic epilepsy, IGE idiopathic generalized epilepsy, JAE juvenile absence epilepsy, y year, mo months.