Table 1 Patient characteristics at baseline

From: Anlotinib plus toripalimab as a first-line treatment in patients with advanced gastric cancer and performance status 2: the phase II APICAL-GC trial

Characteristics

Patients (N = 24)

Age

 Median (Range)

67.5 (41–89)

Sex

 Female

4 (16.7%)

 Male

20 (83.3%)

PS

 Tumor-related PS 2

22 (91.7%)

 Non-tumor-related PS 2

2 (8.3%)

Primary site

 Gastric

24 (100.0%)

 Gastroesophageal junction

0 (0%)

Previous gastrectomy

 Yes

7 (29.2%)

 No

17 (70.8%)

Previous adjuvant chemotherapy

 Yes

4 (16.7%)

 No

20 (83.3%)

Number of metastatic sites

 1

9 (37.5%)

 ≥2

15 (62.5%)

Metastatic site

 Distant lymph node

20 (83.3%)

 Liver

11 (45.8%)

 Lung

6 (25.0%)

 Peritoneum

3 (12.5%)

 Other

4 (16.7%)

MMR status

 dMMR

0 (0%)

 pMMR

24 (100%)

ERBB2 amplification

 Yes

0 (3.3%)

 No

24 (96.7%)

PD-L1 expression

 CPS <1

11 (45.8%)

 CPS ≥1

10 (41.7%)

 Unknown

3 (12.5%)

TMB (Mutation/Mb), median (Range)

8.38 (3.35–27.4)