Table 1 Parameter ranges for generating synthetic single-focal and multi-focal tumor datasets

From: Individualizing glioma radiotherapy planning by optimization of a data and physics-informed discrete loss

Shared Parameters

Parameter

Min

Max

Dw

0.035

0.2

ρ

0.035

0.2

R

10

30

θnecro

0.70

0.85

θup

0.45

0.60

θdown

0.15

0.35

\({T}_{{{\rm{sim}}}}\)

100

—

Single Focal Tumor Center (mm)

(x0, y0, z0)

57.6

96

Multi-Focal Tumor Centers (mm)

Tumor 1 Center (\({x}_{0}^{1},{y}_{0}^{1},{z}_{0}^{1}\))

57.6

96

Tumor 2 Center (\({x}_{0}^{2},{y}_{0}^{2},{z}_{0}^{2}\))

(\({x}_{0}^{1},{y}_{0}^{1},{z}_{0}^{1}\))  ±  9.6

Tumor 3 Center (\({x}_{0}^{3},{y}_{0}^{3},{z}_{0}^{3}\))

(\({x}_{0}^{2},{y}_{0}^{2},{z}_{0}^{2}\))  ±  9.6

  1. All values are given as minimum and maximum.
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