Fig. 6: Expansion and diversification of microbial community structure and function in paired mother-infant. | Nature Communications

Fig. 6: Expansion and diversification of microbial community structure and function in paired mother-infant.

From: Prenatal exposure to trace elements impacts mother-infant gut microbiome, metabolome and resistome during the first year of life

Fig. 6

A Distinct microbial gene profiles (according to KEGG pathway analysis) of the maternal and infant stool metagenomes at different postpartum visits. The relative abundance of pathways in the given sample was colored by its row Z-score (row mean/row SD). The vertical color bar represents the higher-order KEGG module belonging to the corresponding pathway. B Principal coordinate analysis of Bray-Curtis distances based on relative abundances of pathways demonstrates clustering by time point. Statistical test was permutational multivariate analysis of variance with FDR correction for multiple test comparisons, F-value = 1.73, R2 = 0.127. C Enumeration of the observed species within the maternal and infant stool samples. The box ranges from the 25th to the 75th percentile, and the median value (middle line), while the whiskers extend from each quartile to the minimum and maximum values within 1.5 × interquartile range (IQR) of the box. Data points beyond this range are considered outliers (single points). Statistical test was Kruskal–Wallis test with FDR correction for multiple test comparisons, p’ indicated the value before FDR correction, two-tailed. Number of subjects: Infant_First, n = 16; Infant_Second, n = 11; Infant_Third, n = 6; Mother_First, n = 13; Mother_Second, n = 6; Mother_Third, n = 13. Source data are provided as a Source Data file.

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