Fig. 8: Selection of proteins with altered abundance in the ADD patient group. | Nature Communications

Fig. 8: Selection of proteins with altered abundance in the ADD patient group.

From: Enrichment of extracellular vesicles using Mag-Net for the analysis of the plasma proteome

Fig. 8: Selection of proteins with altered abundance in the ADD patient group.The alternative text for this image may have been generated using AI.

Illustration of selected protein-coding genes that are either increased (INPPL1, VPS13A, DNAJC10, S100B, and HTT) or decreased (VCP, MAP2K2, USP15, JMJD6, and CD36) in ADD plasma when compared with the other three disease groups. The analysis represents a pilot cohort of plasma from 40 individuals: 10 with Alzheimer’s disease dementia (ADD); 10 Parkinson’s disease (PD) cognitively normal (PDCN); 10 PD with dementia (PDD); and 10 age-matched healthy and cognitively normal (HCN) individuals.

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