Fig. 2: Cardiac phenotypes of CPT2H-KO mice. | Nature Communications

Fig. 2: Cardiac phenotypes of CPT2H-KO mice.

From: Mitophagy mitigates mitochondrial fatty acid β-oxidation deficient cardiomyopathy

Fig. 2: Cardiac phenotypes of CPT2H-KO mice.The alternative text for this image may have been generated using AI.

a Survival (both male and female) of a cohort of wild-type (n  =  18) and CPT2H-KO (n  =  29) mice. b Quantification of heart weight to body weight ratio (HW/BW) for 4-week-old wild-type (n  =  8) or CPT2H-KO mice (n  =  6). Data represent mean ± s.d. c Representative hematoxylin and eosin (H&E) staining of transverse heart sections from 4-week-old wild-type or CPT2H-KO mice. Scale  = 1 mm. d–f Echocardiographic quantification of percentage fractional shortening (FS) (d), ejection fraction (EF) (e), and left ventricular internal dimension-diastole (LVIDd) (f) for wild-type and CPT2H-KO mice at indicated age (n  =  12). Data represent mean ± s.d. The P-values were calculated using an unpaired two-tailed Student’s t test (b, d–f). Source data are provided as a Source Data file.

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