Table 1 Antibiotic susceptibility profiling of the 4 clinical isolates
From: In-host evolution of Yersinia enterocolitica during a chronic human infection
Antibiogram | ||||||
|---|---|---|---|---|---|---|
Class | Subclass | Antibiotic | Ye.1 | Ye.2 | Ye.3 | Ye.4 |
β-lactam | penicillin (4 G) | piperacillin-tazobactam³ | – | – | – | – |
penicillin (4 G) | piperacillin | – | r | – | – | |
penicillin (4 G) | ticarcillin | R | R | R | R | |
penicillin (3 G) | amoxicillin | R | R | R | R | |
carbapenem | ertapenem | – | – | – | – | |
penicillin | ticarcillin-clavulanate | – | – | – | – | |
cephem (3 G) | ceftazidime | – | r | – | – | |
cephem (2 G) | cefoxitin | – | r | – | R | |
penicillin (4 G) | temocillin | – | r | – | – | |
carbapenem | imipenem | – | r | – | – | |
penicillin (3 G) | amoxicillin-clavulanate | – | r | – | – | |
cephem (3 G) | cefotaxime | – | r | – | – | |
cephem (3 G) | ceftazidime-avibactam | – | r | – | – | |
carbapenem | meropenem | – | – | – | – | |
monobactam | aztreonam | – | – | – | – | |
cephem (4 G) | cefepime | – | – | – | – | |
cephem (3 G) | moxalactam | – | r | – | – | |
penicillin | mecillinam | – | r | – | – | |
cephem (5 G) | ceftolozan-tazobactam | – | r | – | – | |
cephem | cefiderocol | – | r | – | – | |
quinolone | quinolone | nalidixic acid | – | – | R | R |
fluoroquinolone | levofloxacin | – | – | – | – | |
fluoroquinolone | ciprofloxacin² | – | – | – | – | |
tetracycline | tigecycline | – | – | – | – | |
fosfomycin | fosfomycin | – | – | – | – | |
nitrofuran | nitrofurantoin | – | – | – | – | |
sulfonamide-trimethoprime | sulfamethoxazole-trimethoprim | – | – | – | – | |
amphenicol | chloramphenicol | – | – | – | – | |
polymyxin | colistin | – | – | – | – | |
aminoglycosides | gentamicin | – | – | – | – | |
amikacin³ | – | – | – | – | ||
tobramycin | – | – | – | – | ||
netilmicin¹² | – | r | – | – | ||
MIC | ||||||
|---|---|---|---|---|---|---|
Class | Subclass | Antibiotic | Ye.1 | Ye.2 | Ye.3 | Ye.4 |
β-lactam | cephem (3 G) | ceftriaxone¹²³ | 0.047 | 0.094 | 0.094 | > 256 |
cephem (2 G) | cefoxitin | 4 | 12 | 12 | > 256 | |
penicillin (4 G) | piperacillin-tazobactam³ | 0.094 | 0.25 | <0.016 | 0.094 | |
aminoglycosides and aminoglycosides-like | netilmicin¹² | 0.75 | 3 | 0.064 | 0.064 | |
amikacin³ | 3 | 3 | 2 | 1 | ||
tobramycin | 1 | 1 | 0.094 | 0.094 | ||
gentamicin | 0.5 | 1 | 0.094 | 0.094 | ||
spectinomycin | 12 | 24 | 0.094 | 0.094 | ||
Quinolone | fluoroquinolone | ciprofloxacin² (Etest - MH) | 0.008 | 0.012 | 0.002 | 0.032 |
fluoroquinolone | ciprofloxacin² (microdilution - LB) | 0.015 | 0.03 | 0.125 | 0.5 | |
fluoroquinolone | levofloxacin | 0.032 | 0.032 | 0.008 | 0.032 | |
