Fig. 2: Forest plot of the adjusted RlapsRisk BC score HRs on the prediction of 5-year metastasis-free survival on the CANTO cohort. | Nature Communications

Fig. 2: Forest plot of the adjusted RlapsRisk BC score HRs on the prediction of 5-year metastasis-free survival on the CANTO cohort.

From: Deep learning assessment of metastatic relapse risk from digitized breast cancer histological slides

Fig. 2: Forest plot of the adjusted RlapsRisk BC score HRs on the prediction of 5-year metastasis-free survival on the CANTO cohort.The alternative text for this image may have been generated using AI.

Each square of the forest plot represents the HR of the RlapsRisk BC score (a continuous variable) adjusted for the prognostic clinico-pathological factors in the subgroup of patients defined by the variable category in the first column of the table. The 95% HR confidence intervals, computed using the Wald method, are represented by the horizontal lines. Histological tumor grade 1 and low clinical risk group were removed as no MFS events were recorded in these subgroups. Hazard ratios (HRs) and 95% confidence intervals were estimated using a Cox proportional hazards model. p Values correspond to two-sided Wald tests evaluating the null hypothesis HR = 1 and were adjusted for multiple comparisons using the Benjamini–Hochberg procedure. *p < 0.1, **p < 0.05, ***p < 0.01.

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