Table 3 Classification of patients according to each classifier (RlapsRisk BC, Clinical score, and RR Combined)

From: Deep learning assessment of metastatic relapse risk from digitized breast cancer histological slides

 

CANTO validation cohort (N = 1169)

RlapsRisk BC classifier

Clinical score classifier

RR Combined classifier

Number at low riska

893

879

910

Number at high riskb

276

290

259

% of patients with MFS events in the low-risk group

1.56%

1.59%

1.32%

% of patients with MFS events in the high-risk group

8.69%

8.28%

10.04%

Kaplan–Meier’s hazard ratio

5.83

5.51

8.01

95% CI

(3.02–11.28)

(2.85–10.66)

(4.04–15.88)

Log-rank p value

<0.005

<0.005

<0.005

  1. aPredicted probability of 5-year MFS event ≤5%.
  2. bPredicted probability of 5-year MFS event >5%.