Fig. 2: Phage lysis increases the persistence of slower-growing AR cells.
a Representative CLSM images of co-cultures of strains AS (cyan) and ARC,Tet (magenta) (upper images) or of strains AS (cyan) and ARC,Str (magenta) (lower images) in the absence or presence of phage T6. We imaged the biomass after ten days of incubation in the absence of antibiotic pressure. b The proportions of the total biomass areas occupied by strains ARC,Tet or ARC,Str when grown in co-culture with strain AS in the absence or presence of phage T6. c The biomass diameters of strains AS, ARC,Tet and ARC,Str when grown in monoculture in the absence (left) or presence (right) of phage T6. d The biomass diameters of co-cultures of strains AS and ARC,Tet or strains AS and ARC,Str in the absence or presence of phage T6. e The biomass areas (population size) of strain ARC,Tet, when grown in co-culture with strain AS in the absence or presence of phage T6. f The proportions of ARC,Tet cells within co-cultures as a function of the radial distance from the centroid of the biomass. For b–f, each data point is an independent experimental replicate (n = 5), the black data points are for experiments in the absence of phage T6, and the green data points are for experiments in the presence of phage T6. For b–e, the p values are for two-sample two-sided Welch tests. Source data are provided as a Source Data file.
