Table 1 List of genes used in gene signatures

From: Interleukin-35 impairs human NK cell effector functions and induces their ILC1-like conversion with tissue residency features

Gene signatures

Genes Up

Genes Down

NK CD56Bright

LEF1, TCF7, BACH2, TOX2, GZMK, NCR2, CCR7, CD300C, KIT, IL7R, IL9R, RUNX2, ITGA1, IL1R1

ZEB2, ZBTB16, PRDM1, CXCR1, CXCR2, CX3CR1, KIR2DL1, KIR2DL3, KIR3DL1, KIR3DL2, TIGIT, FCGR3A, FCGR3B, S1PR5, CD6, CD160

NK CD56Dim

ZEB2, ZBTB16, PRDM1, CXCR1, CXCR2, CX3CR1, KIR2DL1, KIR2DL3, KIR3DL1, KIR3DL2, TIGIT, FCGR3A, FCGR3B, S1PR5, CD6, CD160

LEF1, TCF7, BACH2, TOX2, GZMK, NCR2, CCR7, CD300C, KIT, IL7R, IL9R, RUNX2, ITGA1, IL1R1

ILC1-like cells

CD9, ITGAE, ITGA1, CXCR4, CXCR3, CXCR6, SMAD7, RGS16

KLF2, LGALS1, ITGA4, PLEK, S1PR5, CD160

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