Table 1 Pregnancy outcomes in women with Marfan syndrome or Loeys–Dietz syndrome following PEARS procedure

										Aortic dimensions (mm)
Patient (pregnancy number)	Underlying Diagnosis	Indication for PEARS	Age at PEARS	Ethnicity	BMI	Chronic hypertension	Delivery type	Beta-blockers during pregnancy	Aortic Dissection related to pregnancy^†	Pre-pregnancy			Post-pregnancy
										AoR^a	Arch^b	DescAo^c	AoR^a	Arch^b	DescAo^c
1 (1)	LDS	AoR 40 mm, future pregnancy	32	Asian	32.3	No	Elective C-section	Yes	No	39	29	17	39	30	18
1 (2)							Elective C-section	Yes	No	41	30	18	40	27	17
2	MFS	AoR 45 mm	22	White	33.7	No	Emergency C-section*	Yes	No	44	28	20	44	27	18
3	MFS	AoR 48 mm	20	White	23.1	No	Elective C-section	No	No	46	35	18	46	35	20
4	MFS	AoR 45 mm	26	White	16.6	No	Elective C-section	Yes	No	43	20	16	41	21	16
5 (1)	MFS	AoR 47 mm	20	White	23.5	No	Vaginal assisted	No	No	47	33	18	47	35	19
5 (2)							Elective C-section	Yes	No	47	35	19	47	35	19
6	MFS	AoR 43 mm, History of AoR dilatation during previous pregnancy	35	White	20.7	No	Vaginal	Yes	No	37	33	18	37	30	22
7	MFS	AoR 42 mm, future pregnancy	32	White	19.7	No	Vaginal	No	No	45	26	18	45	26	18

LDS Loeys–Dietz syndrome, MFS Marfan syndrome, PEARS Personalized External Aortic Root Support, BMI body mass index, AoR aortic root, DescAo descending aorta.
^†Aortic dissection occurring during pregnancy or up to 6 weeks post-partum; ^ap = 0.93; ^bp = 0.96; ^cp = 0.52; the Wilcoxon signed-rank test was used to compare continuous variables. *Spontaneous rupture of membranes and premature labor.

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