Fig. 4: Structure of DSS1–INTAC–PEC. | Nature Communications

Fig. 4: Structure of DSS1–INTAC–PEC.

From: DSS1 is required for proper Integrator–PP2A function

Fig. 4: Structure of DSS1–INTAC–PEC.

a, b Cryo-EM map (a) and molecular model (b) of DSS1-containing INTAC–PEC shown in two different views. Notably, the cryo-EM map is a composite map derived from multibody refinement. c Structural model showed a close-up view of the mRNA (yellow) inserted into the catalytic center of INTS11 (orange). d Structural model showing the conformation of DSS1 in DSS1–INTAC (Gray) and DSS1–INTAC–PEC (INTS7: green, DSS1: magenta).

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