Fig. 2: Synthesis of the dual pump DP•6PF6. The azide56 S1•2PF6 and the bromide60 S2 were dissolved in DMF and heated to 40 °C for 4 h under microwave irradiation to afford S3•3PF6 in 51% yield. | Nature Communications

Fig. 2: Synthesis of the dual pump DP•6PF6. The azide56 S1•2PF6 and the bromide60 S2 were dissolved in DMF and heated to 40 °C for 4 h under microwave irradiation to afford S3•3PF6 in 51% yield.

From: Controlled assembly of rotaxane translational isomers using dual molecular pumps

Fig. 2

The azide S3•3PF6 was subjected to a copper-catalyzed click reaction in DMF with the propargyl ether54,60 S4•3PF6 in the presence of tris[(1-benzyl-1H-1,2,3-triazol-4-yl)methyl]amine (TBTA). After workup the dual pump DP6+ was isolated as a yellow solid in 71% yield as the PF6− salt.

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