Table 1 Baseline (pre-treatment) characteristics of trial participants for all 92 participants

From: Safety and efficacy of 3- and 5-day regimens of levamisole in loiasis: a randomized, placebo-controlled, double-blind clinical trial

 

PLA (N = 30)

LEV-3 (N = 33)

LEV-5 (N = 29)

Sex

 Female

10 (33.3)

10 (30.3)

10 (34.5)

 Male

20 (66.7)

23 (69.7)

19 (65.5)

 Age, mean ± SD

50.1 ± 11.2

46.6 ± 13.1

47.0 ± 13.1

MFD, mf/mL

 Arithmetic mean ± SD

24,796 ± 27,535

16,057 ± 13,168

20,594 ± 28,314

 Minimum; maximum

4240; 113,500

15; 48,935

0/400a; 130,230

 Geometric mean (95% CI)

16,268 (11,721–22,579)

8883 (4974–15,863)

11,607 (7311–18,426)

 Median [IQR]

13,475 [7780–23,805]

12,775 [5695–24,675]

10,850 [6335–21,690]

Mansonella perstans prevalence, N; %

4; 13.1

1; 3.0

3; 10.3

 Heart rate, mean (bpm) ± SD

75 ± 13

79 ± 18

77 ± 12

 Mean blood pressure, mean (mmHg) ± SD

102 ± 15

102 ± 18

103 ± 16

 Systolic blood pressure, mean (mmHg) ± SD

138 ± 22

137 ± 21

139 ± 22

 Diastolic blood pressure, mean (mmHg) ± SD

84 ± 13

84 ± 17

85 ± 15

 Body temperature, mean (°C) ± SD

36.1 ± 0.4

36.2 ± 0.4

36.2 ± 0.5

  1. CI confidence interval, bpm beats per minute, IQR interquartile range, SD standard deviation, MFD Microfilarial density.
  2. a 400 correspond to the minimum MFD after excluding the participant with 0 mf/mL.