Fig. 4: Size effect of 3Asphere on transarterial embolization (TAE) therapy in rabbits bearing VX2 tumor. | Nature Communications

Fig. 4: Size effect of 3Asphere on transarterial embolization (TAE) therapy in rabbits bearing VX2 tumor.

From: Tumor vessel-adaptable adhesive and absorbable microspheres for sustainable transarterial chemoembolization therapy

Fig. 4: Size effect of 3Asphere on transarterial embolization (TAE) therapy in rabbits bearing VX2 tumor.

a Schematic diagram of the experimental schedule. Created in BioRender. BioRender.com/kz59339. b Representative DSA imaging of tumors before and after TAE using 3Asphere-90. c Representative CT-enhanced images. Scale bars: 1 cm. d Relative tumor growth volume (n = 3 rabbits in each group). Statistical analysis was performed using unpaired two-tailed Student’s t-test. e Representative magnetic resonance imaging (MRI) of liver (T1: T1 weighted imaging, T2: T2-weighted imaging, DWI: diffusion-weighted imaging, T1 + : T1 enhanced imaging). Scale bars: 1 cm. f Apparent diffusion coefficient (ADC) (n = 3 rabbits in each group). Statistical analysis was performed using unpaired two-tailed Student’s t-test. g Kaplan-Meier survival curves of tumor-bearing rabbits (n = 3 rabbits in each group). Statistical analysis was performed using a log-rank (Mantel-Cox) test. h Changes in body weight (n = 3 rabbits in each group). Data are presented as mean ± SD. Source data are provided as a Source Data file.

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