Fig. 5: P. canaliculata has a pax6 gene highly expressed in the eye buds.
From: A genetically tractable non-vertebrate system to study complete camera-type eye regeneration
A Domain and 3D-folding predictions for human, D. melanogaster and P. canaliculata pax6 genes. Purple = PAX domain, orange = HOX domain, dark gray = disordered regions (see Supplementary Fig. 6). B Confocal images of pax6 (cyan) and rhodopsin (magenta) HCR during embryonic development. rhodopsin highlights the localization of the retina and the differentiation of the photoreceptors. The images are representative of five embryos. C Confocal images of pax6 (cyan) and nec2 (orange) HCR during embryonic development. nec2, also known as proprotein convertase 2 (pc2) or prohormone convertase 2, has been used as marker for the nervous system. The images are representative of five embryos. D Confocal images of pax6 (cyan) and rhodopsin (magenta) HCR on eye stalk whole mount during adult eye regeneration. The images are representative of five samples. E Detail of the 15 and 21 dpa regenerating retina. White arrowheads highlight cells expressing both pax6 (cyan) and rhodopsin (magenta). The images are representative of five esamples.
