Fig. 2: Nutrients were increased and metabolites were decreased in the faeces of vancomycin-treated mice. | Nature Communications

Fig. 2: Nutrients were increased and metabolites were decreased in the faeces of vancomycin-treated mice.

From: Vancomycin-resistant enterococci utilise antibiotic-enriched nutrients for intestinal colonisation

Fig. 2: Nutrients were increased and metabolites were decreased in the faeces of vancomycin-treated mice.The alt text for this image may have been generated using AI.

a Nutrients that were increased in the faeces of VAN-treated mice (shown in red) compared to H2O-treated mice (shown in blue). b Metabolites that were decreased in the faeces of VAN-treated mice (shown in red) compared to H2O-treated mice (shown in blue). a, b comparison of nutrients and metabolites in the VAN-treated faeces to the H2O-treated faeces used an unpaired t-test (two-sided) with Benjamini-Hochberg FDR, n = 5 mice per group from one independent experiment, with data shown as mean ± SD. c Vancomycin-resistant E. faecium (NCTC 12202) counts were high in the faeces from vancomycin-treated mice (shown in red) and nearly undetectable in the faeces of water-treated mice (shown in blue). Comparisons of the E. faecium plate counts were made using a Mann–Whitney U test (two-sided) of log10-transformed counts. n = 5 mice per group from one independent experiment, with data shown as medians ± IQR. * = P ≤ 0.05, ** = P ≤ 0.01, *** = P ≤ 0.001. VAN vancomycin, H2O water, LOD limit of detection.

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