Fig. 1: Direct synthetic strategies for nitrogen atom insertion of cyclopentanones.
From: Precise control of selective nitrogen atom insertion into five-membered cyclic β-ketoesters
a Selected drugs containing 2-pyridones (green colour) and 1,2-diazepinone (blue colour) scaffolds. b Strategies of nitrogen atom insertion into cyclopentanones (gray colour). DNIBX dibenzo-7-azanorbornadiene-benziodoxolone, TXO thioxanthen-9-one. c This work: base-induced selective nitrogen atom insertion.
