Table 4 Parameters used to simulate vaccination under different efficacy scenarios

From: Modelling transmission of Middle East respiratory syndrome coronavirus in camel populations and the potential impact of animal vaccination

 

Description

Values

Source

rv

Relative infectiousness of vaccinated animals

1% (50% as sensitivity analysis assuming infectiousness is proportional to the logarithm of viral load).

6,7

rinf_v

Relative infectiousness of vaccinated previously infected animals

0.15% (33% as sensitivity analysis assuming infectiousness is proportional to the logarithm of viral load).

6

φv

Relative susceptibility of vaccinated animals

100% (or 75% in scenario 2)

NA. Larger reduction in susceptibility unlikely given all vaccinated previously seronegative animals were infected in refs. 6,7.

φinf_v

Relative susceptibility of vaccinated previously infected animals

75% (or 75% in scenario 2)

NA. Indication of reduced susceptibility6 but unable to reliably quantify in small population

1/ρ

The rate of waning of vaccine-induced effects

1, 3 or 10 years−1