Table 4 Parameters used to simulate vaccination under different efficacy scenarios
Description | Values | Source | |
|---|---|---|---|
rv | Relative infectiousness of vaccinated animals | 1% (50% as sensitivity analysis assuming infectiousness is proportional to the logarithm of viral load). | |
rinf_v | Relative infectiousness of vaccinated previously infected animals | 0.15% (33% as sensitivity analysis assuming infectiousness is proportional to the logarithm of viral load). | |
φv | Relative susceptibility of vaccinated animals | 100% (or 75% in scenario 2) | NA. Larger reduction in susceptibility unlikely given all vaccinated previously seronegative animals were infected in refs. 6,7. |
φinf_v | Relative susceptibility of vaccinated previously infected animals | 75% (or 75% in scenario 2) | NA. Indication of reduced susceptibility6 but unable to reliably quantify in small population |
1/ρ | The rate of waning of vaccine-induced effects | 1, 3 or 10 years−1 |