Fig. 8: GrK+CD103–CD8+ Trm cells accumulate in the brains of AD patients. | Nature Communications

Fig. 8: GrK+CD103–CD8+ Trm cells accumulate in the brains of AD patients.

From: CD103–CD8+ T cells promote neurotoxic inflammation in Alzheimer’s disease via granzyme K–PAR-1 signaling

Fig. 8

a Immunofluorescence staining of control (CTRL) and AD human brain tissues. Scale bar = 40 µm, or 15 µm in the zoomed images. b Bar plots showing the percentage of intraparenchymal CD103–, CD103+, and GrK+CD103– CD8+ T cells in the hippocampus of HCs (n = 3) and AD patients (n = 3). Data are means ± SD (two-tailed Student’s t-test). Source data are provided as a Source Data file. c Bar plots showing the percentage of intravascular CD103–and GrK+CD103– CD8+ T cells in the hippocampus of HCs (n = 3) and AD patients (n = 3). Data are means ± SD (two-tailed Student’s t-test). Source data are provided as a Source Data file.

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