Fig. 1: Validation of RNA Pol-CUT&Tag in the Mtb genome.

A Correlation plot among CUT&Tag biological replicates (n = 3, R1, R2, R3) performed in standard growth (STD) and oxidative stress (OX) conditions. B Principal component analysis (PCA) for the three replicates of each condition. C FRiP analysis. Results are shown as mean ± s.d. of independent biological replicates (n = 3). D Density plot of peaks width distribution. E CUT&Tag mean signal distribution at high confidence peaks. Average plots (top panel) and density heatmaps (bottom panel) of CUT&Tag reads referring to peak center, within ± 1 kb distance. Data referring to STD and OX conditions are shown in blue and orange, respectively. Source data are provided as a Source Data file and supporting data 3.