Fig. 4: MV130 abrogates systemic T2 immune responses in HDM-sensitised mice. | Nature Communications

Fig. 4: MV130 abrogates systemic T2 immune responses in HDM-sensitised mice.

From: A mucosal vaccine prevents eosinophilic allergic airway inflammation by modulating immune responses to allergens in a murine model of airway disease

Fig. 4

a Schematic representation of the model employed to assess in vitro responses of splenocytes from the different groups after HDM stimulation. b Cytokine production after 3 days of stimulation of splenocytes with HDM from the different groups (PBS n = 15, MV130 n = 8, HDM n = 12, HDM + MV130 n = 10 mice; 4 independent experiments). c Ratios of cytokine production (HDM n = 12, HDM + MV130 n = 10 mice; 4 independent experiments). Values are mean ± SEM. Statistical significance was determined using unpaired One-way ANOVA (b), unpaired Kruskal–Wallis (b, IFN-ɣ) and two-side unpaired Student’s t test (c): *p < 0.05, **p < 0.01 and ***p < 0.001. Exact p values and source data are available in the Source Data file.

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