Fig. 1: Low inoculums of modern respiratory A. baumannii clinical isolates result in chronic lung infection in tlr4 mutant mice. | Nature Communications

Fig. 1: Low inoculums of modern respiratory A. baumannii clinical isolates result in chronic lung infection in tlr4 mutant mice.

From: A chronic Acinetobacter baumannii pneumonia model to study long-term virulence factors, antibiotic treatments, and polymicrobial infections

Fig. 1: Low inoculums of modern respiratory A. baumannii clinical isolates result in chronic lung infection in tlr4 mutant mice.

Groups of female C3H/HeN (WT) or C3H/HeJ (tlr4 mutant) mice were intranasally inoculated with 108 G636 (A), 108 G654 (B), 108 Ab19606 (C), 105 G636 (D), 105 G654 (E), or 105 Ab19606 (F). Beginning at 24 hpi, groups of mice were sacrificed every 3 days, and bacteria in the lungs were quantified. Each data point indicates an individual mouse, and the connecting line intersects each timepoint at the mean. The limit of detection (10 CFU) is indicated by the dashed line. Source data are provided as a Source Data file.

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