Fig. 5: Independent validation of the PDAC cfRNA classifier in the separate BCC cohort.
From: Cell free RNA detection of pancreatic cancer in pre diagnostic high risk and symptomatic patients
a PDAC score assigned to each sample in the validation set, separated by diagnosis group (sample size noted underneath each group). Each row is a different experiment, with the first comparing only PDAC and Benign, PDAC and intermediate pathologies in the second row, and all conditions in the bottom row. Boxplots display the 25th, 50th, and 75th percentiles of groups, with whiskers extending up to 1.5 times beyond inter-quartile range. b, c ROC plots based on PDAC score, and associated AUC values, for each analysis condition. Additional ROC plots are shown for stratification of patients by sex (b) and age (c).
