Table 1 T > C conversion rates in liver injury experiment

From: SLAMseq reveals potential transfer of RNA from liver to kidney in the mouse

 

T > C conversion % (median, IQR)

group

mRNA

small RNA

 

liver

kidney

liver

kidney

4TU-negative

0.000 (0.000 - 0.015) *

0.000 (0.000 - 0.023) **

ND

ND

Cre-negative

0.017 (0.000 - 0.116)

0.000 (0.000 - 0.036)

0.056 (0.013 - 0.120)

0.064 (0.019 - 0.118)

labelled in health

1.861 (0.595 - 2.821) **

0.027 (0.000 - 0.065) **

0.210 (0.049 - 0.705)

0.051 (0.000 - 0.099) **

labelled in injury

3.304 (0.938 - 4.630) **

0.053 (0.000 - 0.105) **

0.300 (0.062 - 0.990)

0.046 (0.000 - 0.093) **

4sU

0.000 (0.000 - 0.036) **

0.003 (0.000 - 0.034) **

ND

ND

  1. Rates are expressed as % - i.e. a rate of 1% means conversion of 1 in 100 Ts. ND = not determined. *p = 0.05; **p < 10–12 for comparison to the Cre-negative group within that tissue by two-sided Wilcoxon signed rank test after Kruskal-Wallis rank sum test. Source data are provided as a Source Data file.
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