Table 1 Table of model parameters
From: Episodic transport of protein aggregates achieves a positive size selectivity in aggresome formation
Kinetic parameter | Expression | Parameter | Value | Sourcea |
|---|---|---|---|---|
\({k}_{{{{\rm{on}}}}},{k}_{{{{\rm{on}}}}}^{{\prime} }\) | \({{p}_{0}D}_{{{{\rm{D}}}}}{R}_{{{{\rm{C}}}}}\) | \({p}_{0}\) | 2 × 1018 m−3 | this study |
\({k}_{{{{\rm{off}}}}}\) | \({p}_{0}^{{\prime} }{k}_{{{{\rm{on}}}}}\) | \({p}_{0}^{{\prime} }\) | 0.1 | this study |
\({k}_{1}\) | \({p}_{1}\) | \({p}_{1}\) | 0.0025 s−1 | Fig. 2F |
\({k}_{2}\) | \({p}_{2}/{R}_{{{{\rm{C}}}}}\) | \({p}_{2}\) | 3.33 × 10−9 m s−1 | Fig. 2F |
\({k}_{3}\) | \({p}_{3}{{R}_{{{{\rm{C}}}}}}^{0.5}\) | \({p}_{3}\) | 50.265 m−0.5 s−1 | this study |
\({k}_{4}\) | \({k}_{{{{\rm{on}}}}}{k}_{3}{k}_{6}/({k}_{5}{k}_{{{{\rm{off}}}}})\) | detailed balance | ||
\({k}_{5}\) | \({{p}_{5}{R}_{{{{\rm{C}}}}}}^{2}{k}_{3}\) | \({p}_{5}\) | 5 × 1012 m−2 | this study |
\({k}_{6}\) | \({{p}_{6}k}_{{{{\rm{off}}}}}\) | \({p}_{6}\) | 10−1 to 10−4 | manually set |
\({v}_{{{{\rm{C}}}}}\) | \({p}_{{{{\rm{v}}}}}/{R}_{{{{\rm{C}}}}}\) | \({p}_{{{{\rm{v}}}}}\) | 3 × 10−13 m2 s−1 | Fig. 3F |
