Table 3 Adverse metabolic phenotypes at baseline and the 4YFU

From: Long-term health outcomes in adolescents with obesity treated with faecal microbiota transplantation: 4-year follow-up

 

FMT

Placebo

pCMH

BL

4YFU

pMcN

BL

4YFU

pMcN

Obesitya

26 (100%)

23 (88%)

-

28 (100%)

24 (86%)

-

>0.99

High waist circumferencea

26 (100%)

23 (88%)

-

28 (100%)

26 (93%)

-

0.66

Metabolic syndrome

9 (35%)

7 (28%)

0.72

7 (25%)

12 (43%)

0.13

0.95

Dyslipidaemia

19 (73%)

16 (64%)

0.51

21 (75%)

20 (71%)

>0.99

0.75

Impaired fasting glucose

8 (31%)

9 (36%)

>0.99

9 (32%)

7 (25%)

0.68

0.75

Hypertension

7 (27%)

7 (27%)

>0.99

5 (18%)

10 (36%)

0.23

0.98

Abnormal liver function

9 (35%)

5 (20%)

0.34

5 (18%)

6 (21%)

>0.99

0.48

  1. Data are n (%) and two-sided p values (unadjusted). Adverse phenotypes are defined in ‘Methods’. Within-group differences between baseline (BL) and the 4-year follow-up (4YFU) were assessed using McNemar’s tests (McN) and between-group differences with Cochran–Mantel–Haenszel (CMH) tests.
  2. aAll participants had obesity and high waist circumference at baseline, so only Fisher’s exact tests were used to compare potential between-group differences at the 4YFU.