Fig. 7: Integration of pathomics and cell composition to study the impact of inflammation. | Nature Communications

Fig. 7: Integration of pathomics and cell composition to study the impact of inflammation.

From: FUSION: a web-based application for in-depth exploration of multi-omics data with brightfield histology

Fig. 7: Integration of pathomics and cell composition to study the impact of inflammation.The alternative text for this image may have been generated using AI.

A Uniform Manifold Approximation and Projection (UMAP) plot generated using combined non-tubule cell type composition and morphologic features of glomeruli from acute kidney injury, chronic kidney disease, and reference groups. Selected glomeruli shown from indicated locations. Each dot represents a glomerulus. B–E Same UMAP as in (A) with each dot colored by the content of (B) podocyte, (C) endothelial cell, (D) fibroblast, and (E) immune cell transcripts. Scale bar indicates 25 µm. Source data are provided as a Source Data file.

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