Fig. 4: Role of PemK in pOXA-48 stability.
From: Dissecting pOXA-48 fitness effects in clinical Enterobacterales using plasmid-wide CRISPRi screens
The PemI-PemK TA system promotes pOXA-48 vertical transmission. A Stability of pOXA-48 (darker lines) and pOXA-48∆pemK (lighter dashed lines) in the different clinical strains over 5 days in LB culture (with a daily 1:1000 dilution). B pOXA-48 and pOXA-48∆pemK stability after 24 h of CRISPRi gene silencing of individual plasmid genes.
