Fig. 2: Characterization of VCPIP1 domain functionality in complex with VCP. | Nature Communications

Fig. 2: Characterization of VCPIP1 domain functionality in complex with VCP.

From: Structural basis of VCP-VCPIP1-p47 ternary complex in Golgi maintenance

Fig. 2

First row shows cartoon depictions of VCP in complex with VCPIP1 containing various domain truncations, second row depicts TR-FRET binding results and last row depicts DUB activity results at 62.5 nM enzyme concentration. Dashed grey lines are used to organize data with corresponding VCPIP1 truncation, a VCPIP1WT, b VCPIP1ΔVCPID, c VCPIP1ΔUBX and (d) VCPIP1ΔVCPID ΔUBX, with the corresponding biochemical data.

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