Table 2 Clinical samples used in this study, related to Figs. 2, 5 and 6
Cohort | Donor ID | Sex | Age | No. of doses | Dose | Days since last shot | COVID-19 severity | Sampling days post PCR positivity or onset | Blood collection | HLA-A | HLA-B | HLA-C | |||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
1 | 2 | 3 | |||||||||||||||
C12 + COVID-19 convalescents | DC3 | Male | 61 | Not vaccinated | NA | NA | NA | NA | Moderate | 7 | 2022/3/9 | A*24:02 | A*26:03 | B*39:01 | B*52:01 | C*03:03 | C*12:02 |
DC6 | Female | 30 | x3 | BNT162b2 | BNT162b2 | BNT162b2 | NA | Mild | 10 | 2022/9/5 | A*24:02 | - | B*48:01 | B*52:01 | C*08:03 | C*12:02 | |
IK-40 | Male | 31 | unknown | unknown | unknown | unknown | unknown | Mild | 2 | 2022/1/24 | A*24:02 | A*31:01 | B*35:01 | B*52:01 | C*03:03 | C*12:02 | |
IK-63 | Female | 41 | x2 | unknown | unknown | NA | 195 | Mild | 17 | 2022/4/13 | A*24:02 | - | B*52:01 | - | C*12:02 | - | |
GV33-1 | Male | 40 | x3 | BNT162b2 | BNT162b2 | mRNA-1273 | 477 | Mild | 9 | 2022/10/11 | A*24:02 | - | B*52:01 | B*59:01 | C*01:02 | C*12:02 | |
GV37 | Female | 23 | Not vaccinated | NA | NA | NA | NA | Mild | 17 | 2021/5/20 | A*24:02 | - | B*15:07 | B*52:01 | C*03:03 | C*12:02 | |
GV66 | Male | 35 | x2 | BNT162b2 | BNT162b2 | NA | 176 | Mild | 15 | 2022/3/9 | A*02:01 | A*24:02 | B*40:06 | B*52:01 | C*08:01 | C*12:02 | |
GV69 | Female | 46 | x3 | BNT162b2 | BNT162b2 | mRNA-1273 | 19 | Mild | 19 | 2022/4/18 | A*24:02 | - | B*15:01 | B*52:01 | C*04:01 | C*12:02 | |
GV73 | Male | 42 | x3 | BNT162b2 | BNT162b2 | BNT162b2 | 145 | Mild | 14 | 2022/5/23 | A*11:01 | A*24:02 | B*52:01 | B*54:01 | C*01:02 | C*12:02 | |
GV75 | Male | 38 | x3 | mRNA-1273 | mRNA-1273 | mRNA-1273 | 177 | Mild | 38 | 2022/12/5 | A*24:02 | - | B*52:01 | B*54:01 | C*01:02 | C*12:02 | |
GV88 | Male | 43 | x3 | mRNA-1273 | mRNA-1273 | mRNA-1273 | 146 | Mild | 22 | 2022/9/3 | A*24:02 | - | B*52:01 | - | C*12:02 | - | |
GV90 | Male | 64 | x3 | BNT162b2 | BNT162b2 | BNT162b2 | 153 | Mild | 16 | 2022/8/24 | A*24:02 | A*26:01 | B*40:02 | B*52:01 | C*12:02 | C*15:02 | |
GV92 | Femlae | 33 | x3 | BNT162b2 | BNT162b2 | BNT162b2 | 130 | Mild | 22 | 2022/8/24 | A*24:02 | A*26:01 | B*15:01 | B*52:01 | C*03:03 | C*12:02 | |
GV93 | Male | 33 | x3 | BNT162b2 | BNT162b2 | mRNA-1273 | 111 | Mild | 26 | 2022/8/27 | A*24:02 | - | B*07:02 | B*52:01 | C*07:02 | C*12:02 | |
GV96 | Male | 41 | x3 | BNT162b2 | BNT162b2 | BNT162b2 | 135 | Mild | 26 | 2022/9/3 | A*02:01 | A*24:02 | B*52:01 | B*54:01 | C*01:02 | C*12:02 | |
CAK-1 | Femlae | 86 | unknown | unknown | unknown | unknown | unknown | Moderate | 3 | 2022/1/31 | A*24:02 | - | B*13:01 | B*52:01 | C*03:04 | C*12:02 | |
CAK-2 | Femlae | 84 | unknown | unknown | unknown | unknown | unknown | Mild | 3 | 2022/1/31 | A*24:02 | A*33:03 | B*44:03:01 | B*52:01 | C*12:02 | C*14:03 | |
CAK-5 | Femlae | 68 | unknown | unknown | unknown | unknown | unknown | Mild | 3 | 2022/1/31 | A*24:02 | - | B*52:01 | - | C*12:02 | - | |
CAK-6 | Male | 61 | unknown | unknown | unknown | unknown | unknown | Mild | 3 | 2022/1/31 | A*11:01 | A*24:02 | B*15:01 | B*52:01 | C*04:01 | C*12:02 | |
CAK-8 | Male | 49 | unknown | unknown | unknown | unknown | unknown | Severe | 7 | 2022/1/31 | A*02:07 | A*24:02 | B*46:01 | B*52:01 | C*01:02 | C*12:02 | |
CAK-18 | Female | 72 | x2 | unknown | unknown | NA | unknown | Moderate | 2 | 2022/2/16 | A*02:01 | A*24:02 | B*35:01] | B*52:01 | C*03:04 | C*12:02 | |
CAK-21 | Male | 74 | Not vaccinated | NA | NA | NA | NA | Severe | 9 | 2022/3/2 | A*24:02 | - | B*40:01 | B*40:02 | C*03:04 | C*12:02 | |
CAK-24 | Male | 34 | Not vaccinated | NA | NA | NA | NA | Severe | 18 | 2022/3/2 | A*02:01 | A*24:02 | B*52:01 | B*67:01:02 | C*07:02 | C*12:02 | |
AK-20 | Female | 58 | Not vaccinated | NA | NA | NA | NA | Severe | 10 | 2021/9/3 | A*24:02 | - | B*52:01 | - | C*12:02 | - | |
C12- COVID-19 convalescents | GV36 | Male | 40 | x3 | BNT162b2 | BNT162b2 | mRNA-1273 | 160 | Mild | 15 | 2022/8/3 | A*02:06 | A*24:02 | B*07:02 | B*51:01 | C*07:02 | C*14:02 |
GV61 | Female | 39 | x2 | mRNA-1273 | mRNA-1273 | NA | 159 | Mild | 20 | 2022/3/2 | A*24:02 | - | B*07:02 | B*54:01 | C*01:02 | C*07:02 | |
GV63 | Male | 34 | x3 | BNT162b2 | BNT162b2 | BNT162b2 | 61 | Mild | 16 | 2022/2/24 | A*02:01 | A*24:02 | B*54:01 | - | C*01:02 | - | |
GV64 | Female | 67 | Not vaccinated | NA | NA | NA | NA | Moderate | 24 | 2022/3/2 | A*24:02 | - | B*40:02 | B*54:01 | C*01:02 | C*03:03 | |
GV65 | Male | 41 | x3 | BNT162b2 | BNT162b2 | NA | 318 | Mild | 10 | 2022/3/3 | A*24:02 | A*26:01 | B*40:02 | B*51:01 | C*15:02 | - | |
GV82 | Male | 45 | x3 | BNT162b2 | BNT162b2 | BNT162b2 | 215 | Mild | 24 | 2022/8/10 | A*11:01 | A*24:02 | B*15:18 | - | C*07:04 | C*08:01 | |
GV83 | Male | 38 | x3 | BNT162b2 | BNT162b2 | BNT162b2 | 125 | Mild | 24 | 2022/8/12 | A*11:01 | A*26:01 | B*35:01 | B*40:02 | C*03:04 | - | |
GV84 | Male | 30 | x3 | mRNA-1273 | mRNA-1273 | mRNA-1273 | 104 | Mild | 16 | 2022/8/12 | A*11:01 | A*33:03 | B*44:03 | B*67:01:01 | C*07:02 | C*14:03 | |
GV85 | Female | 46 | x3 | BNT162b2 | BNT162b2 | BNT162b2 | 228 | Mild | 13 | 2022/8/12 | A*02:01 | A*26:01 | B*40:02 | B*54:01 | C*01:02 | C*03:04 | |
GV86 | Male | 63 | x3 | mRNA-1273 | mRNA-1273 | mRNA-1273 | 125 | Mild | 32 | 2022/8/20 | A*11:01 | A*24:02 | B*44:03 | B*67:01:01 | C*07:02 | C*14:03 | |
GV87 | Female | 51 | x3 | mRNA-1273 | mRNA-1273 | mRNA-1273 | 139 | Mild | 23 | 2022/8/20 | A*02:06 | A*26:03 | B*35:01 | B*51:01 | C*03:03 | C*03:04 | |
GV89 | Female | 46 | x3 | mRNA-1273 | mRNA-1273 | mRNA-1273 | 202 | Mild | 29 | 2022/8/23 | A*02:01 | A*24:02 | B*51:01 | B*67:01:01 | C*07:02 | C*14:02 | |
GV91 | Female | 62 | x3 | BNT162b2 | BNT162b2 | BNT162b2 | 138 | Mild | 15 | 2022/8/24 | A*02:06 | A*26:01 | B*15:01 | - | C*03:03 | C*04:01 | |
GV94 | Female | 46 | x3 | BNT162b2 | BNT162b2 | BNT162b2 | 203 | Mild | 24 | 2022/9/3 | A*24:02 | A*31:01 | B*15:01 | B*51:01 | C*04:01 | C*14:02 | |
GV95 | Female | 41 | x3 | BNT162b2 | BNT162b2 | BNT162b2 | 146 | Mild | 25 | 2022/9/3 | A*02:06 | - | B*51:01 | B*59:01 | C*01:02 | C*14:02 | |
GV97 | Male | 39 | x3 | BNT162b2 | BNT162b2 | BNT162b2 | 251 | Mild | 15 | 2022/9/6 | A*02:01 | A*24:02 | B*15:01 | B*46:01 | C*01:02 | C*03:03 | |
GV98 | Female | 41 | x3 | BNT162b2 | BNT162b2 | BNT162b2 | 226 | Mild | 16 | 2022/9/7 | A*11:01 | A*33:03 | B*44:03:01 | B*54:01 | C*01:02 | C*14:03 | |
IK-33 | Male | 41 | unknown | unknown | unknown | unknown | unknown | Mild | 34 | 2021/9/6 | A*26:01 | A*31:01 | B*40:01 | B*40:02 | C*03:03 | C*07:02 | |
IK-34 | Male | 38 | unknown | unknown | unknown | unknown | unknown | Mild | 46 | 2021/9/16 | A*02:06 | A*02:07 | B*07:02 | B*46:01 | C*01:02 | C*07:02 | |
IK-36 | Male | 61 | unknown | unknown | unknown | unknown | unknown | Mild | 2 | 2022/1/28 | A*03:01 | A*24:02 | B*15:01 | B*44:02 | C*03:03 | C*05:01 | |
IK-41 | Female | 29 | unknown | unknown | unknown | unknown | unknown | Mild | 1 | 2022/1/26 | A*24:02 | A*31:01 | B*35:01 | - | C*03:03 | - | |
IK-46 | Male | 25 | x2 | unknown | unknown | NA | unknown | Mild | 26 | 2022/2/9 | A*24:02 | A*33:03 | B*54:01 | B*58:01 | C*01:02 | C*03:02 | |
IK-47 | Male | 36 | x2 | unknown | unknown | NA | unknown | Mild | 10 | 2022/2/10 | A*02:01 | A*24:02 | B*15:01 | B*40:06 | C*08:01 | - | |
IK-48 | Male | 75 | unknown | unknown | unknown | unknown | unknown | Mild | 12 | 2022/2/26 | A*24:02 | - | B*40:01/10 | B*52:01 | C*04:01 | C*12:02 | |
IK-50 | Male | 63 | unknown | unknown | unknown | unknown | unknown | Moderate | 14 | 2022/2/14 | A*24:02 | A*26:03 | B*15:01 | B*46:01 | C*01:02 | C*03:03 | |
IK-54 | Male | 35 | x2 | unknown | unknown | NA | unknown | Mild | 21 | 2022/2/25 | A*02:01 | A*24:02 | B*15:18 | B*54:01 | C*01:02 | - | |
IK-56 | Male | 43 | x2 | unknown | unknown | NA | unknown | Mild | 29 | 2022/3/2 | A*02:01 | A*02:03 | B*46:01 | B*58:01 | C*01:02 | C*03:02 | |
IK-57 | Male | 47 | Not vaccinated | NA | NA | NA | NA | Mild | 42 | 2022/3/10 | A*02:01 | A*33:03 | B*44:03 | B*46:01 | C*03:03 | C*14:03 | |
CAK-3 | Male | 74 | unknown | unknown | unknown | unknown | unknown | Moderate | 4 | 2022/1/31 | A*02:06 | A*24:02 | B*51:01 | - | C*14:02 | - | |
CAK-13 | Female | 88 | unknown | unknown | unknown | unknown | unknown | Mild | 9 | 2022/2/9 | A*11:01 | A*24:02 | B*54:01 | B*55:02 | C*01:02 | C*03:03 | |
CAK-20 | Male | 79 | unknown | unknown | unknown | unknown | unknown | Moderate | 18 | 2022/3/2 | A*24:02 | A*33:03 | B*15:01 | B*55:02 | C*01:02 | C*04:01 | |
DC-1 | Male | 44 | unknown | unknown | unknown | unknown | unknown | Mild | 7 | 2022/2/28 | A*24:02 | A*33:03 | B*07:02 | B*44:03:01 | C*07:02 | C*14:03 | |
DC-2 | Male | 78 | unknown | unknown | unknown | unknown | unknown | Mild | 10 | 2022/3/3 | A*24:02 | - | B*07:02 | - | C*07:02 | - | |
AK-18 | Female | 25 | Not vaccinated | NA | NA | NA | NA | Moderate | 10 | 2021/9/3 | A*24:02 | A*26:01 | B*40:02 | B*40:06 | C*03:04 | - | |
AK-19 | Male | 47 | Not vaccinated | NA | NA | NA | NA | Severe | 11 | 2021/9/3 | A*11:01 | A*31:01 | B*35:01 | B*51:01 | C*03:03 | C*14:02 | |
AK-24 | Female | 28 | Not vaccinated | NA | NA | NA | NA | Severe | 13 | 2021/9/8 | A*02:03 | A*24:02 | B*46:01 | B*48:01 | C*01:02 | C*08:01 | |
AK-25 | Female | 42 | Not vaccinated | NA | NA | NA | NA | Severe | 7 | 2021/9/8 | A*24:02 | A*26:01 | B*40:06 | B*54:01 | C*01:02 | C*08:01 | |
AK-32 | Male | 57 | Not vaccinated | NA | NA | NA | NA | Moderate | 10 | 2021/9/13 | A*02:01 | - | B*13:01 | B*15:01 | C*03:03 | C*03:04 | |
C12+ seronegative | GV13 | Male | 23 | x3 | BNT162b2 | BNT162b2 | mRNA-1273 | NA | NA | NA | 2022/3/11 | A*24:02 | A*26:02 | B*15:01 | B*52:01 | C*03:03 | C*12:02 |
GV19 | Male | 24 | x2 | BNT162b2 | BNT162b2 | NA | 2021/6/30 | A*24:02 | A*26:01 | B*52:01 | B*59:01 | C*01:02 | C*12:02 | ||||
GV20 | Female | 24 | x2 | BNT162b2 | BNT162b2 | NA | 2021/6/30 | A*02:06 | A*24:02 | B*35:01 | B*52:01 | C*08:01 | C*12:02 | ||||
GV22 | Male | 23 | x2 | BNT162b2 | BNT162b2 | NA | 2021/6/30 | A*24:02 | - | B*51:01 | B*52:01 | C*12:02 | C*14:02 | ||||
GV33-2 | Male | 40 | x3 | BNT162b2 | BNT162b2 | mRNA-1273 | 2021/7/5 | A*24:02 | - | B*52:01 | B*59:01 | C*01:02 | C*12:02 | ||||
C12- seronegative | GV9 | Female | 24 | x2 | BNT162b2 | BNT162b2 | NA | NA | NA | NA | 2021/6/29 | A*24:02 | A*26:01 | B*40:01 | B*54:01 | C*01:02 | C*03:04 |
GV15 | Female | 23 | x2 | BNT162b2 | BNT162b2 | NA | 2021/6/29 | A*24:02 | - | B*40:02 | B*54:01 | C*01:02 | C*15:02 | ||||
GV17 | Male | 24 | x2 | BNT162b2 | BNT162b2 | NA | 2021/6/29 | A*11:01 | A*26:01 | B*40:01 | B*54:01 | C*01:02 | C*04:01 | ||||
GV72 | Female | 20 | x2 | mRNA-1273 | mRNA-1273 | NA | 2022/5/10 | A*26:01 | A*33:03 | B*40:02 | B*44:03:01 | C*03:04 | C*14:03 | ||||
