Fig. 8: Proposed model by which CFP1 regulates GC responses. | Nature Communications

Fig. 8: Proposed model by which CFP1 regulates GC responses.

From: CFP1 promotes germinal center affinity maturation and restrains memory B cell differentiation through H3K4me3 modulation

Fig. 8: Proposed model by which CFP1 regulates GC responses.

A Cfp1 deficiency impairs GC commitment and leads to premature exit of GCB cells to differentiate into plasma cells and memory B cells. B Molecular mechanisms of Cfp1-mediated regulation of GC response through expression of GCB-related genes indirectly or directly through H3K4me3 modification. See text for details.

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