Fig. 3: Antibiotic resistance and capsule loci analysis of ST167 HC20 clusters.

a Bar graph depicting the number of genomes within each HC20 cluster. The colour is representative of HC20 cluster, red is 109409 and blue is 64736. b Bar graph showing the percentage of genomes isolated from human sources from each HC20 cluster. c Bar graph demonstrating the percentage of genomes from each HC20 cluster that carry the respective antibiotic resistance genes displayed on the x-axis (source data in Supplementary Data 2). The category of Trim/Sulf is representative of trimethoprim and sulfonamide antibiotic classes. The annotation of gyrA/parC denotes the chromosomal mutations of gyrA_D87N, gyrA_S83L, parC_S80I and parE_S458A. d Sequence comparison of KL124G1 Kaptive 2.0 reference and NZ_CP083869.1 as a representative strain, visualised with Easyfig; the level of nucleotide sequence conservation is indicated by shading based on the legend. Capsule locus genes were annotated using Kaptive reference gene locus tags. IS elements were identified with ISfinder.