Fig. 2: Covalent Occupancy Kinetics Enrichment via Proteomics (COOKIE-Pro) workflow using spebrutinib and its desthiobiotin probe SB-2 as an example.
From: COOKIE-Pro: covalent inhibitor binding kinetics profiling on the proteome scale

Created in BioRender. Lin, H. (2025) https://BioRender.com/3zmk1a2.