Fig. 6: Overview of the analyses.

Process of fitting the compartmental transmission model and generating the outbreak simulations based on different vaccination scenarios. UKHSA UK Health Security Agency, CPRD Clinical Practice Research Datalink, COVER Cover of Vaccination Evaluated Rapidly. The transmission model was stratified by region, age groups and vaccine status. The model includes 12 age groups: <1, 1–2, 2–3, 3–4, 4–5, 5–6, 6–10, 10–15, 15–20, 20–30, 30–40, 40+.