Table 1 Comparison of seismic with other MAGMA-based cell-type association methods
From: Disentangling associations between complex traits and cell types with seismic
seismic | scDRS | FUMA | S-MAGMA | |
|---|---|---|---|---|
No gene thresholding based on trait association | ✓ | ✓ | ✓ | |
No gene thresholding based on cell-type expression | ✓ | ✓ | ✓ | |
Accounts for gene expression variability | ✓ | ✓ | ||
Scalable runtime | ✓ | ✓ | ✓ | |
Tool includes results visualizations | ✓ | ✓ | ✓ | |
Identifies cell-type level influential genes | ✓ |
