Fig. 3: CryoEM structure of Ang2-5A12.6DS Fab complex. | Nature Communications

Fig. 3: CryoEM structure of Ang2-5A12.6DS Fab complex.

From: Disulfide-constrained Fabs overcome target size limitation for high-resolution single particle cryoEM

Fig. 3

A CryoEM map of Ang2-5A12.6DS Fab complex at a resolution of 2.7 Å with Ang2 in pink, Fab HC in yellow, and LC in light gray. B CryoEM map of Ang2-5A12.6DS complex colored by local resolution. EM density for the entire Ang2-5A12.6DS complex (C) and selected map regions (D–G) illustrating high resolution features, with Ang2 in magenta, RTX LC in gray, and HC in yellow.

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