Fig. 2: Heterogeneity of population event dynamics.
a Sample population events from different slices. For events recorded in voltage clamp, vertical scale bar denotes 0.2 nA. For events recorded in current clamp, vertical scale bar denotes 10 mV. Sample events marked in lavender (aperiodic) and green (periodic), are exemplar events marked throughout figure. b Power spectra for marked cells from the dataset to the left, averaged over all of the events seen. There is a clear peak in the power spectrum, here at ~ 6 Hz. Power spectra are normalized to have maximum value 1. c The power spectra for the event periods of the entire dataset. Power spectra are normalized to have maximum value 1. Data sorted by full width at half max (for those without peaks), and then by peak location (for those with peaks). Arrows denote marked data from (a). d Histogram of the peak location for peaked power spectra. e Same data as (c), sorted and grouped by slice, rather than by width. f Scatterplot of the peak location for pairs of cells. Since some of the collected data measures excitatory currents, some measures inhibitory currents, and some measures mixtures, there is no natural categorization for choosing which cell is “Cell 1” and which is “Cell 2”. These labels are chosen at random for this figure. The reported correlation coefficient is the median of the distribution of correlation coefficients computed for different instantiations of the randomization. Dashed ellipse denotes the 95% confidence interval. Periodic data from (a) marked as a green square. g Same as (c) for the nonevent portions of the data.
