Fig. 5: Top 24 tissues expression of ESRRG and ESRRA.

a, b Violin plots of expression values of ESRRG and ESRRA across tissue types, with brain tissues shown in yellow and non-brain tissues shown in lilac. The P-value indicates a significantly higher proportion of brain tissues overexpressing ESRRG compared to ESRRA. Box plots display the median (center line) and the interquartile range (box; 25th-75th percentiles). Points appearing outside of the boxes correspond to outliers above or below 1.5 times the interquartile range. The expression of the top 24 tissue types, out of 54 available, are shown. Gene expression levels for each tissue were obtained from the GTEx Analysis Release V10 (dbGAP Accession phs000424.v10.p2) via the GTEx Portal (accessed 11/22/2024). ESRRA = estrogen-related receptor alpha; ESRRG = estrogen-related receptor gamma; GTEx = genotype-tissue expression; TPM = transcripts per million.