Fig. 6: Antibacterial activity and potential mechanism of 6-seleno-GTP.
From: The mechanism of thioamide formation by the YcfA-YcfC system in 6-thioguanine biosynthesis
a MICs of 6-Seleno-GTP and 6-Thio-GTP against ESKAPE pathogens are shown. Blue arrows indicate MICs exceeding the highest tested concentration. b KEGG pathway enrichment analysis of differentially expressed genes is presented. Red represents upregulation; blue represents downregulation. c, d Venn diagrams show the overlap between differentially expressed genes (transcriptomics) and proteins (proteomics). c Nine upregulated genes were identified in both datasets. d One downregulated gene was identified in both datasets. Source data are provided as a Source Data file.
